Here is what's confirmed. Both players entered Saturday as questionable after Friday's final injury report, and both are now out for the 4:25 PM ET kickoff in Miami on CBS. Underdog NFL lists Brown's injuries as ankle and knee and Henderson's as an illness.
Brown's week went the wrong way. He was limited Wednesday with the ankle, then missed Thursday's practice when his knee flared up. He came off injured reserve on Oct. 17 after a high-ankle sprain, so this is the second time this season the ankle has cost him games.
Henderson also sat out Thursday's practice. He suffered a high-ankle sprain of his own against the Raiders on Oct. 11, and the illness listing is new.
What is still open: whether either absence goes past this week. Nobody has reported an IR move for either player, and the Patriots have given no timeline.
For RSO owners, get both out of your lineup now. The game kicks off in the late afternoon window, so if you have a Brown or Henderson slot to fill, you can still pick from the 1 PM players or anyone available in the late games.