Saquon Barkley will miss a second straight game with a hamstring strain when the Eagles host Carolina on Sunday. Will Shipley landed on injured reserve with a foot injury, leaving Dameon Pierce and Carson Steele as the only healthy backs.
DK Metcalf missed Friday's practice with an illness and is questionable for Sunday's game against the Buccaneers. Rico Dowdle is also questionable with a toe injury, but he practiced fully Friday.
Chicago listed running back Kyle Monangai as out for Week 6 after he missed every practice this week with thumb and toe injuries. Ben Johnson says he is trending in the right direction and will not go on injured reserve.
Carolina moved running back Trevor Etienne off injured reserve on Friday, and Dave Canales says he will be active against the Eagles. With AJ Dillon ruled out, Etienne slots in behind Chuba Hubbard.
Todd Monken said Friday that the rookie receiver will play against Baltimore after his Week 5 head injury. Concepcion carries no game status for Week 6, so owners can plan to use him again.
Mike LaFleur said Friday that the rookie's left ankle keeps him out Sunday, and Tyler Allgeier starts with Bam Knight behind him. The coach said there has been no discussion of injured reserve.
Schefter and Rapoport both have Philadelphia adding the former Dallas practice-squad quarterback on Friday. McKee remains the expected starter Sunday against Carolina with Hurts out.
Indianapolis cut the veteran receiver on Friday morning, less than four weeks after signing him. A knee injury kept him out of Week 5, and he never suited up for the Colts.
Seattle's tight end left Thursday Night Football in Denver after a shoulder injury late in the second quarter. Beat writers Gregg Bell and John Boyle confirmed the team's doubtful designation while the Seahawks trailed.
San Francisco designated the veteran receiver to return from injured reserve on Thursday, starting his 21-day activation window. With Deebo Samuel and Demarcus Robinson out for Week 6, Kirk could step into a thin receiver room quickly.
Baltimore's quarterback is officially out of Thursday's session after sitting Wednesday. With two missed practices this week, Tyler Huntley is the more likely Week 6 starter.
Kyle Shanahan said Samuel's hamstring strain made him an IR candidate, but the Week 8 bye lets San Francisco keep him active and wait. Evans missed the first practice of the week with Achilles soreness and a rib injury.
Philadelphia started the 21-day practice clocks Wednesday for guard Landon Dickerson (knee), tight ends Grant Calcaterra and Eli Stowers, and defensive back Jakorian Bennett. All four remain on injured reserve until the club activates them.
Andy Reid held the Chiefs receiver out of the first practice after Kansas City's bye. Rice has not practiced since hurting the hamstring in Week 4 against the Raiders.
The rookie receiver returns to practice Wednesday after missing every game since Week 1 with an ankle injury. Breece Hall and Adonai Mitchell remain week to week.