Sunday NFL preview: London opens Week 5, 49ers–Seahawks lead late window

Sunday's Week 5 NFL schedule begins in London at 9:30 a.m. Eastern and ends with Baltimore visiting Atlanta at 8:20 p.m. The middle of the day includes eight 1 p.m. games and a three-game late window, with several prominent offenses working through injuries before kickoff.

Philadelphia faces Jacksonville at Tottenham Hotspur Stadium in the morning game on NFL Network. The Eagles enter 2-2 against the 3-1 Jaguars, with Saquon Barkley, DeVonta Smith and Marquise Brown ruled out. Philadelphia does get tight end Dallas Goedert, tackle Fred Johnson and linebacker Zack Baun back, according to the team's Friday injury report.

The Eagles released their official London matchup preview Saturday.

The 1 p.m. slate has Cincinnati at Miami, Las Vegas at New England, Minnesota at New Orleans, Cleveland at the New York Jets, Indianapolis at Pittsburgh, Houston at Tennessee, the New York Giants at Washington, and Chicago at Green Bay. FOX carries Bengals–Dolphins, Vikings–Saints, Giants–Commanders and Bears–Packers; CBS has the other four matchups, with regional availability depending on the viewer's market.

Minnesota takes a 4-0 record into New Orleans, while Houston and Tennessee meet with both teams 0-4. Cincinnati receivers Ja'Marr Chase and Tee Higgins are officially active against Miami, resolving their earlier questionable designations. Chase had been listed with a concussion and Higgins with groin and neck injuries.

Personnel update, 12:07 p.m. Eastern, October 11

The official Sunday reports also list Minnesota's Justin Jefferson, Las Vegas running back Ashton Jeanty and Washington receiver Terry McLaurin as active. Vikings receiver Jordan Addison and Steelers running back Rico Dowdle are inactive. New Orleans running back Alvin Kamara and Indianapolis receiver Keenan Allen are active. These are game-day availability decisions; they do not establish snap counts or final results.

Denver visits the Chargers at 4:05 p.m. on CBS. The 0-4 Chargers placed quarterback Trey Lance and offensive lineman Trevor Penning on injured reserve Saturday, while activating Scott Matlock and Branson Taylor. Denver has ruled out cornerbacks Patrick Surtain II and Riley Moss.

Two FOX games follow at 4:25 p.m.: Detroit at Arizona and San Francisco at Seattle. The unbeaten 49ers face the 3-1 Seahawks at Lumen Field. San Francisco activated Mykel Williams from the physically unable to perform list Saturday and removed him from the injury report, but Nick Bosa is out. Seattle has ruled out running back Zach Charbonnet.

The night game on NBC and Peacock sends the 3-1 Ravens to the 2-2 Falcons. Tyler Huntley starts for Baltimore with Lamar Jackson ruled out because of an ankle injury. The Ravens also list center Cam Jurgens and outside linebacker Trey Hendrickson as out. Atlanta downgraded defensive end Za'Darius Smith to out Saturday.

Dallas has already completed its Week 5 matchup with Tampa Bay on Thursday. Buffalo and the Los Angeles Rams play Monday at 8:15 p.m. Eastern, so they are outside Sunday's 13-game slate. Game times and injury designations here reflect the official schedule and reports available at 12:07 p.m. Eastern Sunday.

Sources

NFL: Week 5 viewing schedule · NFL: Week 5 injury designations · NFL: Saturday roster and injury updates · Eagles.com: Eagles at Jaguars injury report, Week 5 · NFL: Current Sunday personnel decisions · NFL: Official Week 5 inactives · CBS Sports: Current inactive tracker