Barkley will miss a second straight game with a hamstring strain. He did not practice this week, so Friday's ruling settles what the week had pointed toward.
Shipley's move is the bigger change to the depth chart. He hurt his foot in the Week 5 loss to Jacksonville in London, and the IR placement means he will miss at least four weeks. With both backs out, Dameon Pierce and Carson Steele are the only healthy running backs on the active roster. Jaydon Blue and Ian Wheeler are on the practice squad.
The rest of the roster is banged up as well. Jalen Hurts is already out with a blood clot in his calf, which leaves Tanner McKee at quarterback. Defensive back Michael Carter (abdomen) and edge rusher Jalyx Hunt (knee, ankle) are also out, and A.J. Epenesa (back) is doubtful. Guard Landon Dickerson, center Drew Kendall and tight ends Grant Calcaterra and Eli Stowers are questionable. DeVonta Smith is not on the game-status list.
What is confirmed: Barkley is out for Sunday, and Shipley is on injured reserve. What is still open: how Philadelphia splits the carries between Pierce and Steele, and whether it elevates Blue or Wheeler from the practice squad before kickoff.
For RSO owners, Barkley is a bench this week with no long-term change to his value or contract plans. Hamstrings can linger, so check his practice reports next week before you count on him for Week 7. Pierce is the most useful short-term start or add, though a backup quarterback and a banged-up line cap his ceiling. Steele is a deep-league flier. Shipley owners can move him to an IR slot if your league allows it.
