What is confirmed
The Colts put out a one-line announcement: "We have released WR Darius Slayton." The team gave no reason and did not announce a corresponding roster move with it.
Slayton never played a game for Indianapolis. The Colts signed him on Sept. 22, and he did not appear in a game over the next few weeks. He first showed up on the practice report on Oct. 9 with a knee injury he picked up in practice that day, and the team ruled him out for the Week 5 game against Pittsburgh the next afternoon.
The team has not given an update on the knee since then, and it did not mention the injury in Friday's announcement.
Why it matters for RSO rosters
Slayton entered the league in 2019, so as a vested veteran he should go straight to free agency rather than through waivers. Any team can sign him once he is healthy enough to pass a physical.
For the Colts, the move takes a name off a receiver depth chart that was already thin in Week 5, when Ashton Dulin was out and Nick Westbrook-Ikhine was elevated from the practice squad. It does not change much for the top of the room, since Slayton had not earned any targets there.