What is confirmed
Moore will not play in Week 6. Schefter added that receiver Joshua Palmer is active, and Garafolo listed defensive tackle Ed Oliver among the Bills inactives again. RotoWire also logged Moore as out for the second week in a row.
This is the same shoulder that flared up in the Week 4 game against New England. Moore sat out Monday night's game at the Rams, then missed practice Wednesday and Thursday this week while the team stayed in California between its two West Coast games.
What is still open
Buffalo has not put a timeline on the injury or talked about an injured reserve move. The schedule helps here. The Bills are off in Week 7, so Moore gets close to two more weeks of rest before Buffalo plays again.
What RSO owners should do now
Keep Moore out of any Week 6 lineup decisions that are still open, since the late games have not started. Do not cut him, and do not sell low. One more missed game followed by a bye is a short-term hit, and his RSO contract value rests on what he gives you in the second half of the season.
If you need a receiver this week, Palmer is the Buffalo name with a path to more targets on Sunday, but he is playing through a shoulder issue of his own and was limited in practice. Treat him as a short-term fill-in, not a long-term add.